Synterex

The Curb-Cut Effect and AI-Driven Medical Writing: Accessibility by Design

By Synterex / September 30, 2024 /

The curb-cut effect refers to the broad and often unexpected benefits of designing for accessibility. Originally intended to assist people with physical disabilities, curb cuts have since proven beneficial for many others—parents with strollers, delivery workers with carts, and even travelers with rolling luggage. This concept extends beyond physical infrastructure to digital tools, including technology-enabled…

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The Challenges and Benefits of Implementing e-Consent in Clinical Trials

By Synterex / September 25, 2024 /

As clinical trials evolve in the digital age, e-consent has emerged as a promising tool to enhance patient engagement, streamline processes, and improve regulatory compliance. While the benefits of e-consent are significant, implementing this technology also presents several challenges that sponsors and clinical teams must navigate. Below, we’ll explore both the benefits and challenges of…

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The Flip Side of Lean Authoring: Navigating the Complexities of Cross-Functional Negotiation

By Synterex / September 15, 2024 / Comments Off on The Flip Side of Lean Authoring: Navigating the Complexities of Cross-Functional Negotiation

Lean authoring, a method popularized by medical writing expert Gregory Cuppan, emphasizes streamlined, focused writing that delivers key messages without unnecessary detail. It promises efficiency, but the reality of implementing lean authoring within a cross-functional team often involves substantial negotiation. Lean authoring becomes not a black-or-white process but, rather, an exercise in grayscale methodology. This…

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Project Deadlines, Dynamic Demands, Work-Stress! YOGA to the Rescue

By Synterex / September 12, 2024 / Comments Off on Project Deadlines, Dynamic Demands, Work-Stress! YOGA to the Rescue

Deadlines to meet, projects to juggle, and dynamic demands? Work can be stressful at times. It’s no wonder people feel anxious and overwhelmed. Well, that’s when you might want to spend some time on a yoga mat! Physical and mental health are strongly related, and their relationship is well described in literature, too. Frequent stress…

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Remote Rx: Writing from Home – Perks & Challenges

By Synterex / September 9, 2024 / Comments Off on Remote Rx: Writing from Home – Perks & Challenges

In today’s ever-evolving work environment, shaped by the aftermath of the COVID-19 pandemic, the once-standard 9-to-5 office routine is rapidly becoming obsolete. This shift is ushering in the era of remote work, with various professions embracing change seamlessly. Among them, medical writing stands out as particularly well suited to adapting to this new way of…

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Key Considerations for Submitting Your NDA or BLA to FDA on a Rolling Basis

By Synterex / September 6, 2024 / Comments Off on Key Considerations for Submitting Your NDA or BLA to FDA on a Rolling Basis

Establishing early alignment with the FDA on the rolling submission approach is pivotal to your success. Before you initiate any submission activities, ensure you have secured the FDA’s agreement on both the timing and the scope of your rolling submission. This early communication ensures that there are no surprises later and allows both you and…

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Chronicles of Drug Development and FDA: Review, Approve, Monitor

By Synterex / September 3, 2024 / Comments Off on Chronicles of Drug Development and FDA: Review, Approve, Monitor

For a drug to get on the market in the United States, it must go through a rigorous review by FDA’s Center for Drug Evaluation and Research (CDER) (or, in some cases, the Center for Biologics Evaluation and Research [CBER]). Drugs are tested in preclinical and then in clinical settings to assess safety and efficacy.…

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Best Practices for Managing Information Requests from Health Authorities

By Synterex / August 31, 2024 / Comments Off on Best Practices for Managing Information Requests from Health Authorities

Managing information requests from health authorities such as the FDA is a critical aspect of regulatory compliance for pharmaceutical companies. These interactions can directly affect the pace of your product’s approval process. To succeed, it’s important to follow best practices that focus on clarity, accuracy, and efficient project management. A key component to success is…

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Biosimilar Laughs: A Chuckle in Every Dose

By Synterex / August 28, 2024 / Comments Off on Biosimilar Laughs: A Chuckle in Every Dose

What is a Biosimilar? In the scientific realm, biosimilars, akin to their reference products, are biologic medications. Approval for biosimilars hinges on demonstrating no clinically significant differences in safety and efficacy compared to the reference products. Picture them as biological siblings, crafted from the same sources as live cells or microbes, ensuring the same safety…

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10 Most Common Risks to Your BLA or NDA Timeline (and How to Mitigate Them)

By Synterex / August 25, 2024 / Comments Off on 10 Most Common Risks to Your BLA or NDA Timeline (and How to Mitigate Them)

When pursuing a Biologics License Application (BLA) or New Drug Application (NDA), meeting timelines is crucial. However, the path to approval is often fraught with potential delays. Understanding these risks—and knowing how to mitigate them—can make or break your timeline. Here are the 10 most common risks and expert tips on how to manage them…

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